Xiaoyong Bao


  • 1038 Citations
  • 19 h-Index
If you made any changes in Pure, your changes will be visible here soon.

Personal profile

Personal profile

Dr. Bao is an Associate Professor of Pediatrics in the Division of Clinic and Experimental Immunology and Infectious Disease. She received her PhD in the Cellular Physiology and Molecular Biophysics from the University of Texas Medical Branch in Galveston. Dr. Bao continued her education as a J.Kempner scholar for the year 2003-2004 and completed her postdoctoral fellowship in a NIAID-supported T32 training program for emerging and reemerging infectious in UTMB. One of her research interests focuses on biological roles of small non-coding RNAs (sncRNAs), especially the newly discovered sncRNA derived from tRNA, in response to viral infection and environmental stimuli. Biological function studies of sncRNAs are a burgeoning field of interdisciplinary research that crosses the path from chemistry, molecular biology, bioinformatics and computer sciences. The ultimate goal of her sncRNA research is to control viral replication or stress-induced cellular responses by regulating the expression of sncRNAs. Her other research interests include identifying the mechanisms associated with immune evasion of respiratory syncytial virus (RSV) and human metapneumovirus (hMPV), the two leading causes of lower respiratory tract infection in children, and developing therapeutic molecules and attenuated vaccine candidates to combat or prevent these two viral infections.

Research interests

The research in my lab focuses on molecular mechanisms underlying the pathogenesis and host immune responses associated with RSV and hMPV infections, the two leading causes of lower respiratory tract infections in infants. We aim to identify antiviral pathways, viral evasion mechanisms, and roles of sncRNAs in RSV/hMPV infection. The ultimate goal of our research is to develop effective preventive and therapeutic strategies against respiratory virus-associated viral replication and inflammation.

Fingerprint Fingerprint is based on mining the text of the experts' scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

  • 31 Similar Profiles
Metapneumovirus Medicine & Life Sciences
Human metapneumovirus Agriculture & Biology
Connexin 43 Medicine & Life Sciences
Antiviral Agents Medicine & Life Sciences
Respiratory Syncytial Viruses Medicine & Life Sciences
Infection Medicine & Life Sciences
Epithelial Cells Medicine & Life Sciences
Proteins Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Projects 2012 2020

Research Output 1997 2018

  • 1038 Citations
  • 19 h-Index
  • 37 Article
  • 1 Chapter

Exchange Proteins Directly Activated by cAMP and Their Roles in Respiratory Syncytial Virus Infection

Choi, E. J., Ren, Y., Chen, Y., Liu, S., Wu, W., Ren, J., Wang, P., Garofalo, R., Zhou, J. & Bao, X., Nov 15 2018, In : Journal of virology. 92, 22

Research output: Contribution to journalArticle

Respiratory Syncytial Virus Infections
Respiratory Syncytial Viruses
virus replication
1 Citations

Human metapneumovirus small hydrophobic protein inhibits interferon induction in plasmacytoid dendritic cells

Bao, X., Kolli, D., Esham, D., Velayutham, T. S. & Casola, A., Jun 1 2018, In : Viruses. 10, 6, 278.

Research output: Contribution to journalArticle

Dendritic Cells
TNF Receptor-Associated Factor 6
Interferon Type I
1 Citations

Detection of nuclear protein profile changes by human metapneumovirus M2-2 protein using quantitative differential proteomics

Ren, Y., Choi, E., Zhang, K., Chen, Y., Ye, S., Deng, X., Zhang, K. & Bao, X., Dec 1 2017, In : Vaccines. 5, 4, 45.

Research output: Contribution to journalArticle

Nuclear Proteins
PDZ Domains
8 Citations

Identification of two novel functional tRNA-derived fragments induced in response to respiratory syncytial virus infection

Zhou, J., Liu, S., Chen, Y., Fu, Y., Silver, A. J., Hill, M. S., Lee, I., Lee, Y. S. & Bao, X., Jul 1 2017, In : Journal of General Virology. 98, 7, p. 1600-1610 11 p., 000852.

Research output: Contribution to journalArticle

Respiratory Syncytial Virus Infections
Transfer RNA
Respiratory Syncytial Viruses
Virus Replication
9 Citations

Functional motifs responsible for human metapneumovirus M2-2-mediated innate immune evasion

Chen, Y., Deng, X., Deng, J., Zhou, J., Ren, Y., Liu, S., Prusak, D. J., Wood, T. & Bao, X., Dec 1 2016, In : Virology. 499, p. 361-368 8 p.

Research output: Contribution to journalArticle

Immune Evasion
Antiviral Agents
TNF Receptor-Associated Factor 5