John Allen

  • 2512 Citations
  • 19 h-Index
20032019
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  • 4 Similar Profiles
G-Protein-Coupled Receptors Medicine & Life Sciences
Receptor, Serotonin, 5-HT2A Medicine & Life Sciences
Ligands Medicine & Life Sciences
Arrestin Medicine & Life Sciences
Serotonin Medicine & Life Sciences
Receptor, Serotonin, 5-HT2C Medicine & Life Sciences
Leydig Cells Medicine & Life Sciences
Schizophrenia Medicine & Life Sciences

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Projects 2018 2019

Research Output 2003 2019

Orphan Receptor GPR88 as an Emerging Neurotherapeutic Target

Ye, N., Li, B., Mao, Q., Wold, E. A., Tian, S., Allen, J. & Zhou, J., Jan 16 2019, In : ACS Chemical Neuroscience. 10, 1, p. 190 200 p., 10.1021/acschemneuro.8b00572.

Research output: Contribution to journalArticle

G-Protein-Coupled Receptors
Ligands
Brain
Pharmaceutical Preparations
Pharmacology

Synthesis and pharmacological evaluation of non-catechol G protein biased and unbiased dopamine D1 receptor agonists

Wang, P., Felsing, D., Chen, H., Raval, S., Allen, J. & Zhou, J., Apr 5 2019, (Accepted/In press) In : ACS Medicinal Chemistry Letters. 10.1021/acsmedchemlett.9b00050, 10.1021/acsmedchemlett.9b00050.

Research output: Contribution to journalArticle

Open Access
Dopamine D1 Receptors
Dopamine Agonists
GTP-Binding Proteins
Arrestin
Dopamine
2 Citations (Scopus)

Biophysical validation of serotonin 5-HT2A and 5-HT2C receptor interaction

Felsing, D., Anastasio, N., Miszkiel, J. M., Gilbertson, S. R., Allen, J. & Cunningham, K., Aug 1 2018, In : PLoS One. 13, 8, e0203137.

Research output: Contribution to journalArticle

Receptor, Serotonin, 5-HT2C
Receptor, Serotonin, 5-HT2A
serotonin
Serotonin
receptors

Biophysical validation of serotonin 5-HT2A and 5-HT2C receptor interaction

Felsing, D., Anastasio, N., Miszkiel, J., Gilbertson, S. R., Allen, J. & Cunningham, K., Aug 29 2018, In : PLoS One. 13 , 8, 13(8):e0203137.

Research output: Contribution to journalArticle

Open Access
Receptor, Serotonin, 5-HT2C
Receptor, Serotonin, 5-HT2A
serotonin
Serotonin
receptors

Impaired β-arrestin recruitment and reduced desensitization by non-catechol agonists of the D1 dopamine receptor

Gray, D., Allen, J., Mente, S., O'Connor, R., Kozak, R. & Ehlers, M., Feb 14 2018, In : Nature Communications. 9, 674, | DOI: 10.1038/s41467-017-02776-7.

Research output: Contribution to journalArticle

Open Access
Arrestin
Dopamine D1 Receptors
dopamine
Catechols
Pharmacokinetics