• 2674 Citations
  • 30 h-Index
1994 …2023
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Fingerprint Fingerprint is based on mining the text of the experts' scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

  • 3 Similar Profiles
Glutamate Carboxypeptidase II Medicine & Life Sciences
Derivatives Chemical Compounds
Proteins Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
Therapeutics Medicine & Life Sciences
Protease Inhibitors Medicine & Life Sciences
Structure-Activity Relationship Medicine & Life Sciences
Pharmacology Medicine & Life Sciences

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Projects 2012 2023

Research Output 1994 2019

1 Citations

Allosteric Modulation of Class A GPCRs: Targets, Agents, and Emerging Concepts

Wold, E. A., Chen, J., Cunningham, K. & Zhou, J., Oct 1 2019, In : Journal of Medicinal Chemistry. 62, 1, p. 88-127 40 p.

Research output: Contribution to journalArticle

G-Protein-Coupled Receptors
Drug Discovery
Pharmaceutical Chemistry
Drug Delivery Systems
Clinical Trials
2 Citations

Design, Synthesis, and Characterization of 4-Undecylpiperidine-2-carboxamides as Positive Allosteric Modulators of the Serotonin (5-HT) 5-HT2C Receptor

Wild, C. T., Miszkiel, J. M., Wold, E. A., Soto, C. A., Ding, C., Hartley, R. M., White, M., Anastasio, N., Cunningham, K. & Zhou, J., Oct 1 2019, In : Journal of Medicinal Chemistry. 62, 1, p. 288-305 18 p.

Research output: Contribution to journalArticle

Receptor, Serotonin, 5-HT2C
Serotonin
Cocaine
Serotonin 5-HT2 Receptor Agonists
Allosteric Site

Effect of N-(2-aminoethyl) ethanolamine on hypertrophic scarring changes in vitro: Finding novel anti-fibrotic therapies

Chen, Z., Gu, J., El Ayadi, A., Oberhauser, A., Zhou, J., Sousse, L., Finnerty, C., Herndon, D. & Boor, P. J., Jan 1 2019, In : Toxicology and Applied Pharmacology. 362, p. 9-19 11 p.

Research output: Contribution to journalArticle

Ethanolamine
Hypertrophic Cicatrix
Cicatrix
Fibroblasts
Extracellular Matrix
2 Citations

Efficacy of novel highly specific bromodomain-containing protein 4 inhibitors in innate inflammation–driven airway remodeling

Tian, B., Liu, Z., Litvinov, J., Maroto, R., Jamaluddin, M., Rytting, E., Patrikeev, I., Ochoa, L., Vargas, G., Motamedi, M., Ameredes, B., Zhou, J. & Brasier, A. R., Jan 1 2019, In : American journal of respiratory cell and molecular biology. 60, 1, p. 68-83 16 p.

Research output: Contribution to journalArticle

Airway Remodeling
Inflammation
Toll-Like Receptor 3
Histone Acetyltransferases
Myofibroblasts

Orphan Receptor GPR88 as an Emerging Neurotherapeutic Target

Ye, N., Li, B., Mao, Q., Wold, E. A., Tian, S., Allen, J. A. & Zhou, J., Jan 16 2019, In : ACS Chemical Neuroscience. 10, 1, p. 190-200 11 p.

Research output: Contribution to journalReview article

G-Protein-Coupled Receptors
Ligands
Brain
Pharmaceutical Preparations
Pharmacology