• 2216 Citations
  • 26 h-Index
1980 …2016
If you made any changes in Pure, your changes will be visible here soon.

Personal profile

Training Experience

1975 - 1980Ph.D. Biochemistry at North Carolina State University, North Carolina, United States
1971 - 1975B.A. Biology at Quinnipiac University, Connecticut, United States

Personal profile

Member, Institute for Human Infections & Immunity

Research Interests

We are investigating in vivo models of gene/protein expression by the respiratory pathogen Streptococcus pneumoniae and facultative intracellular bacteria (Francisella tularensis, Shigella flexneri, Salmonella typhimurium). In addition, our research group is investigating alterations in gene/protein expression and alterations to the virulence potential of S. pneumoniae in low shear and microgravity environments. We are also interested in the novel methods to detect antibiotic resistance in bacteria and moving our patented method to commercial use.

Keywords

  • Streptoccocus Pneumoniae
  • Gene Expression
  • Antibiotic Resistance

Fingerprint Fingerprint is based on mining the text of the experts' scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

  • 11 Similar Profiles
Shigella flexneri Medicine & Life Sciences
HeLa Cells Medicine & Life Sciences
Bacteria Medicine & Life Sciences
Salmonella typhimurium Medicine & Life Sciences
Interferons Medicine & Life Sciences
Salmonella Medicine & Life Sciences
Virulence Medicine & Life Sciences
Lipoproteins Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Projects 2007 2016

Research Output 1980 2016

  • 2216 Citations
  • 26 h-Index
  • 62 Article
  • 2 Conference contribution
  • 1 Chapter
  • 1 Letter
1 Citations

Spaceflight and spaceflight analogue induced responses in gram positive bacteria

Castro, S. L., Niesel, D., Barrila, J. & Ott, C. M., Jan 1 2016, Effect of Spaceflight and Spaceflight Analogue Culture on Human and Microbial Cells: Novel Insights into Disease Mechanisms. Springer New York, p. 283-296 14 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Space Flight
Gram-Positive Bacteria
organisms
Spacecraft
bacteria
3 Citations
Chloramphenicol Resistance
Electrospray ionization
Electrospray Ionization Mass Spectrometry
antibiotics
Liquid chromatography
4 Citations

PharmaSat: Drug dose response in microgravity from a free-flying integrated biofluidic/optical culture-and-analysis satellite

Ricco, A. J., Parra, M., Niesel, D., Piccini, M., Ly, D., McGinnis, M., Kudlicki, A., Hines, J. W., Timucin, L., Beasley, C., Ricks, R., McIntyre, M., Friedericks, C., Henschke, M., Leung, R., Diaz-Aguado, M., Kitts, C., Mas, I., Rasay, M., Agasid, E. & 4 othersLuzzi, E., Ronzano, K., Squires, D. & Yost, B., 2011, Proceedings of SPIE - The International Society for Optical Engineering. Vol. 7929. 79290T

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Microgravity
Dose-response
microgravity
Nanosatellites
nanosatellites
4 Citations

Global transcription profiling and virulence potential of Streptococcus pneumoniae after serial passage

Pandya, U., Sinha, M., Luxon, B. A., Watson, D. A. & Niesel, D., Aug 15 2009, In : Gene. 443, 1-2, p. 22-31 10 p.

Research output: Contribution to journalArticle

Serial Passage
Streptococcus pneumoniae
Virulence
Gene Expression
Genes
31 Citations

Levofloxacin rescues mice from lethal intra-nasal infections with virulent Francisella tularensis and induces immunity and production of protective antibody

Klimpel, G. R., Eaves-Pyles, T., Moen, S. T., Taormina, J., Peterson, J., Chopra, A., Niesel, D., Carness, P., Haithcoat, J. L., Kirtley, M. & Nasr, A. B., Dec 9 2008, In : Vaccine. 26, 52, p. 6874-6882 9 p.

Research output: Contribution to journalArticle

Francisella tularensis
Levofloxacin
Nose
Antibody Formation
Immunity

Activities 1980 2014

  • 9 Types of External academic engagement - Membership of external research organization

UTMB Development Board

David Niesel (Other)
Jan 2014Dec 2014

Activity: Other activity typesTypes of External academic engagement - Membership of external research organization

Executive Administrative Group

David Niesel (Other)
Jan 2014Dec 2014

Activity: Other activity typesTypes of External academic engagement - Membership of external research organization

Institute for Translational Science Executive Committee

David Niesel (Other)
20132014

Activity: Other activity typesTypes of External academic engagement - Membership of external research organization

Medical Discovery News

David Niesel (Other)
20072014

Activity: Other activity typesTypes of External academic engagement - Membership of external research organization

AAMC GREAT

David Niesel (Member)
19972014

Activity: Other activity typesTypes of External academic engagement - Membership of external research organization

Prizes

Graduate Student Organization Award for Student Advocacy

David Niesel (Recipient), 2001

Prize: Prize (including medals and awards)

J.P. Saunders Endowed Professorship

David Niesel (Recipient), 1999

Prize: Prize (including medals and awards)

President’s Cabinet Award

David Niesel (Recipient), 2009

Prize: Prize (including medals and awards)