Sealy Center for Environmental Health Medicine

Organization profile

Organization profile

Director:  Cornelis J. Elferink, PhD  

Deputy Director:  Lawrence C. Sowers, PhD

 

The mission of the Sealy Center for Environmental Health Medicine, AKA UTMB Center in Environmental Toxicology (UTMB-CET) is to explore the environmental basis of human diseases by fostering collaborative interactions amongst multidisciplinary basic and clinical investigators pursuing both fundamental and translational research pertinent to the effects of environmental factors on human health. The UTMB-CET is housed at the University of Texas Medical Branch in Galveston, and is the only NIEHS environmental health center located on the Gulf of Mexico coast, near the nation's busiest shipping port (Port of Houston) and an expansive petrochemical refining and manufacturing infrastructure. Our proximity to sources of many significant environmental problems makes UTMB a compelling site for such an environmental health sciences center. The underlying causes of these problems include the composition of the natural environment, meteorological conditions (namely hurricanes), population density, personal and commercial transportation patterns, and the endemic petrochemical industry. Some of the most serious environmental issues are ozone pollution, emissions of fine particulates, hazardous chemical releases, hazardous waste sites, and PCB/dioxin contamination of the marine biota. The UTMB-CET investigators concentrate their efforts in three disease categories: 1) asthma pathogenesis; 2) environmentally-linked carcinogenesis; and 3) disease states induced by reactive oxygen stress.

Organization profile

Director:  Cornelis J. Elferink, PhD  

Deputy Director:  Lawrence C. Sowers, PhD

 

The mission of the Sealy Center for Environmental Health Medicine, AKA UTMB Center in Environmental Toxicology (UTMB-CET) is to explore the environmental basis of human diseases by fostering collaborative interactions amongst multidisciplinary basic and clinical investigators pursuing both fundamental and translational research pertinent to the effects of environmental factors on human health. The UTMB-CET is housed at the University of Texas Medical Branch in Galveston, and is the only NIEHS environmental health center located on the Gulf of Mexico coast, near the nation's busiest shipping port (Port of Houston) and an expansive petrochemical refining and manufacturing infrastructure. Our proximity to sources of many significant environmental problems makes UTMB a compelling site for such an environmental health sciences center. The underlying causes of these problems include the composition of the natural environment, meteorological conditions (namely hurricanes), population density, personal and commercial transportation patterns, and the endemic petrochemical industry. Some of the most serious environmental issues are ozone pollution, emissions of fine particulates, hazardous chemical releases, hazardous waste sites, and PCB/dioxin contamination of the marine biota. The UTMB-CET investigators concentrate their efforts in three disease categories: 1) asthma pathogenesis; 2) environmentally-linked carcinogenesis; and 3) disease states induced by reactive oxygen stress.

Fingerprint The fingerprint is based on mining the text of the scientific documents related to the associated persons. Based on that an index of weighted terms is created, which defines the key subjects of research unit

Asthma Medicine & Life Sciences
Hydrogen Sulfide Medicine & Life Sciences
Inflammation Medicine & Life Sciences
DNA Repair Medicine & Life Sciences
Proteins Medicine & Life Sciences
Respiratory Syncytial Virus Infections Medicine & Life Sciences
DNA Medicine & Life Sciences
Antiviral Agents Medicine & Life Sciences

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Projects 2016 2022

Research Output 2003 2018

  • 398 Citations
  • 10 h-Index
  • 76 Article
  • 8 Review article
  • 2 Letter
  • 1 Short survey

Alcohol-induced hepatic steatosis: A comparative study to identify possible indicator(s) of alcoholic fatty liver disease

Fernando, H., Bhopale, K. K., Kondraganti, S. S., Kaphalia, B. & Ansari, G., Feb 16 2018, In : Journal of Drug and Alcohol Research. 7, 236040.

Research output: Contribution to journalArticle

Alcoholic Fatty Liver
Alcoholic Liver Diseases
Alcohols
Diet
Liver

Amelioration of endotoxin-induced inflammatory toxic response by a metal chelator in rat eyes

Shoeb, M., Zhang, M., Xiao, T., Syed, M. & Ansari, N., Jan 1 2018, In : Investigative Ophthalmology and Visual Science. 59, 1, p. 31-38 8 p.

Research output: Contribution to journalArticle

Poisons
Uveitis
Chelating Agents
Endotoxins
Metals
Gene encoding
P-Glycoprotein
Haplotypes
Placenta
Genes