Sciex TripleTOF 5600+ System

Equipment/facility: Equipment

  • Location

    301 University Boulevard Galveston, TX 77555-3579

    United States

Description

Typically used for proteomics, the Sciex TripleTOF 5600+ System is a hybrid quadrupole TOF platform, accurate mass (<3ppm), high-resolution (30,000) system than can operate by means of information-dependent acquisition (IDA) with speed (up to 50Hz) and sensitivity of a TOF MS and quantification capabilities similar to a triple quadrupole MS. When operated in a data-independent acquisition (DIA) mode, termed SWATH-MS by Sciex, the 5600 offers quantitative accuracy comparable to Selected Reaction Monitoring (SRM), and multiplexing capabilities comparable to DDA proteomics. In SWATH-MS, peptide precursors are sequentially selected in defined precursor ion mass windows for concurrent fragmentation, and the resulting fragment ion spectra are recorded in recursive cycles over the chromatography time.

Details

NameSciex TripleTOF 5600+ System
ManufacturersSciex

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Ions
Chromatography
Multiplexing
Peptides
Monitoring
Proteomics
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